Glyphosate interferes with the essential amino acids pathway in plants

Zach Bush:  Glyphosate has interrupted and interfered with the essential amino acids plants were providing to humans.  
 
How did it do this?  It did it thru blocking an enzyme pathway called the shikimate pathway.
 
Wikipedia:  
The shikimate pathway (shikimic acid pathway) is a seven step metabolic route used by bacteria, archaea, fungi, algae, some protozoans, and plants for the biosynthesis of folates and aromatic amino acids (phenylalanine, tyrosine, and tryptophan). 
 
This pathway is not found in animals and humans.  Animals and humans require these amino acids.  Hence the products of this pathway represent essential amino acids.  They must be obtained from organisms which are not animals; or, from animals whose diet includes lower organisms who do have the shikimate pathway and can make these amino acids.
 
 
Monsanto claims Roudup is safe because it interferes with an enzyme pathway only present in  bacteria, archaea, fungi, algae, some protozoans, and plants .
 
So Gly kills the pathway in plants that makes teh essential amino acids humans need. 
 
He details the snowballing effects on infants of loss of healthy bacterial biome. 
 
He says if you go 100% organic, in three weeks, some chronic symptoms begin backing off. 
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Moringa

Moringa as nutrition https://www.youtube.com/watch?v=L9tdLn_Zk1M

Moringa as soap.  https://www.youtube.com/watch?v=FvxWEw3ekLg

 

 

 

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Clinical Experience of Integrative Autism treatment with imuno

Clinical-Experience-of-Integrative-Autism-treatment-with-imuno-28Feb19

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AutismOne 2017

AutismOne 2017

Good discussion of 47 strains

How products and diet need to be addressed

A glimpse into what is involved with bravo and rerum.

Antonucci’s discussions of Rerum and Autism

https://www.youtube.com/watch?v=aKtRqm-CSfM&t=2025s

Rheinwald

https://www.youtube.com/watch?v=LccFsfN_RgI

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563157/

New Brain Lymphatic Vessels Drain Old Concepts

The brain has traditionally been considered an immune privileged organ, in part due to the lack of evidence for lymphatic vasculature (Galea et al., 2007). Two centuries ago, the existence of lymphatic vessels on the surface of the human brain was proposed but it has since been widely dismissed (Lukic et al., 2003). Therefore, while T cells leave all other organs via the lymphatic system to reach nearby lymph nodes, the prevailing view has been that infiltrated T cells exit the brain via venous blood circulation, circumventing the lymph nodes (Ransohoff and Engelhardt, 2012). The recent evidence for the existence of a lymphatic vascular system in the brain’s meninges provided independently by two labs, first by the Kipnis lab (Louveau et al., 2015) and then by the Alitalo lab (Aspelund et al., 2015), challenges this view and raises the intriguing possibility of an alternative gateway for T cells to egress the brain.

The key for identifying these meningeal lymphatic vessels by both labs was the use of a whole-mount preparation where the meninges were fixed while still attached to the skull, thus enabling the preservation of fine meningeal vessels. Kipnis’ lab identified a rather simple network of narrow vessels with a distinct lumen that ran along the blood vessels in the superior sagittal and transverse sinuses on the top of the brain and importantly, expressed multiple molecular hallmarks of lymphatic endothelial cells including lymphatic vessel endothelial hyaluronan receptor 1 (Lyve-1) and vascular endothelial growth factor receptor 3 (VEGFR3). Alitalo’s lab additionally described that this lymphatic network becomes more extensive at the base of the brain, where it contains lymphatic valves, and exits the skull alongside the cranial nerves. The anatomical and cellular classification of these meningeal vessels was strengthened by complimentary experiments from both labs demonstrating functional implications of VEGFR3. Injections of a VEGFR3 ligand, VEGF-c, into the cerebrospinal fluid (CSF) resulted in an increased diameter of the meningeal lymphatic vessels. Conversely, mice with impaired VEGFR3-VEGF-c signaling showed a complete absence of meningeal lymphatic vessels indicating that these vessels, like peripheral lymphatic vessels, are functionally regulated by VEGFR3.

An essential functional characteristic of lymphatic vasculature is permissiveness to fluid and drainage to lymph nodes. In line with this, dyes injected into the CSF were detected both in the lumen of Lyve-1-expressing vessels and in the deep cervical lymph nodes (dcLN), whereas dyes administered in the blood were not. Ligation of the lymphatic vessels above the dcLN completely abolished drainage of dye to these lymph nodes and additionally, increased the diameter of the meningeal lymphatic vessels, indicating that these vessels drain to the dcLN. The Alitalo lab further demonstrated that dye injected into the brain parenchyma was absorbed by lymphatic vessels and preferentially drained into the ipsilateral dcLN from the base of the brain. Surprisingly, Kipnis’ lab excluded the best-known route of drainage into the dcLN, via the nasal cavity’s cribriform plate and the nasal mucosa (Kida et al., 1995), as they failed to see dcLN drainage of dye injected into the nasal mucosa. In contrast, the Alitalo lab’s elaborate imaging studies indicated that lymphatic vessels indeed pass through the skull in the meningeal lining of the cribriform plate and into the nasal mucosa, corroborating the nasal drainage route as one of many possible passages to the dcLN. Hence, future research will be required to map out the extent of this newly discovered lymphatic system and its relationship to the rest of the lymphatic circuitry in the body. This may be particularly important given that disrupting drainage of excess fluids in the peripheral lymphatic system leads to peripheral lymphedema which affects millions of people worldwide. Interestingly, blocking drainage to the dcLN has been shown to exacerbate ischemic-evoked edema in rats (Si et al., 2006), raising the question whether the meningeal lymphatic system plays a critical role in reducing brain edema. This possibility should be considered in future scientific discussions both in basic and clinical sciences.

One intriguing question that remains is whether the lymphatic vessels act as a cellular afferent route out of the brain, allowing T cells to circulate through the meninges and to the dcLN. In their study, Kipnis’ lab observed a ten-fold higher density of T cells that aligned within the lumen of Lyve-1-expressing vessels compared to that of blood vessels. Importantly, removal of the dcLN increased the density of T cells in the meninges, indicating that drainage to the dcLN might be crucial for T cells to egress. While these data suggest that meningeal lymphatic vessels contain T cells, more experiments are necessary to demonstrate whether T cells indeed are circulating via these vessels. Interestingly, metastasis from primary brain tumors (e.g., gliomas) has been found in the dcLN (Mondin et al., 2010), supporting the notion of a direct cellular route. It would be very interesting to investigate the flow of T cells in meningeal lymphatic vessels during infection and inflammation and to determine fluctuation in number of T cells drawn to (and out of) the brain parenchyma which potentially would change our understanding of T cell circulation in the brain.

The functional implications of this newly discovered lymphatic network in both health and disease are broad and raise many exciting questions. Of particular interest would be how this newly discovered meningeal lymphatic system relates to the recently described glymphatic system, which potentiates waste clearance from the brain by facilitating the flux of CSF across the brain parenchyma (Iliff et al., 2012). It will be interesting to investigate if and how pathological agents, such as amyloid β are transported between the glymphatic and lymphatic systems. For example, would removal of amyloid β and other misfolded proteins from the brain parenchyma be reduced in mice with an impaired meningeal lymphatic system (e.g., following removal of the dcLN or in VEGFR3-deficient mice)? Do meningeal lymphatic defects correlate with or cause enhanced risk of patients developing neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease?

Arguably the most appealing aspect of the existence of meningeal lymphatic vessels is the insight it provides about the circulation of T cells in the brain. Immune cells and immune-related molecules are increasingly recognized to play crucial roles in brain wiring in both development and disease. Interestingly, Kipnis’ lab has previously shown that removal of dcLN can induce learning and memory impairments in mice (Radjavi et al., 2014), suggesting that disrupting T cell circulation has gross behavioral consequences. Mapping the cellular lymphatic route and understanding its potential role in behavioral paradigms such as learning and memory, sleep, and stress will advance our understanding of communication between the central nervous system and the immune system. Furthermore, elucidating a potential path for T cell circulation could potentially unveil new therapeutic targets for interventions in neurodegenerative diseases and neurological disorders, including those considered to be triggered by inflammatory responses, such as multiple sclerosis.

These exciting new findings have reopened the discussion about to what degree the brain is immune privileged by revealing a potential lymphatic gateway for T cells to egress the brain.

Aspelund A., Antila S., Proulx S.T., Karlsen T.V., Karaman S., Detmar M., Wiig H., Alitalo K. A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. J. Exp. Med. 2015;212:991–999.  [PubMed]

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Autism Summary of References

This is a page of various deeper topics.  Each one will lead to another page rather than making a book here.

Dr. Ruggiero the inventor of Bravo Yogurt and imuno has been the Keynote Speaker at AutismOne Conference for many years.

Rerum (German manufacture) was replaced by imuno (New Zealand manufacture) in late summer of 2018.

🙂
Mimi

2015

AutismOne Conference 2015 – Dr. Marco Ruggiero’s presentation

Around minute 40 when he talks about the protocol, this is what inspired me to make Bravo Protocol Caps available for sale.

2016

AutismOne Conference 2106 – Dr. Marco Ruggiero’s presentation

2017

AutismOne Conference 2017

2018

AutismOne Conference 2018

2019

2/28/19 Clinical-Experience-of-Integrative-Autism-treatment-with-imuno-28Feb19

AutismOne Conference 2019 – May Chicago

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Bravo & Imuno for Autism

 

 

Imuno research with Autism

Clinical-Experience-of-Integrative-Autism-treatment-with-imuno-28Feb19

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Black Seed: Cumin Oil

Black Cumin: The Magical Egyptian Herb for Allergies, Asthma, and Immune Disorders  by Peter Schleicher, M.D. and Mohamed Saleh, MD

Black Cumin Book.jpeg

This remarkable “black seed” has had a very rich traditional history over the centuries, containing over 100 compounds, including vitamins, trace elements, antioxidants, and essential fatty acids. It has a spicy, pungent, nutty flavor and aroma with notes of black peppercorns.

I started with Black Seed oil and dabbed a drop of oil onto each of my endocrines each day.  I don’t always take everything when I travel, however, my body “let me know” right away how important my black cumin oil was!  I now use it as a daily supplement as dabs to each of the endocrines.   It keeps me very balanced and my mood buoyant.

Purchase VERY fresh Black Cumin here

 

alternate links to the book.

https://www.evernote.com/shard/s99/res/066a103a-bc5e-4d5c-80da-d0af2f6d9cd3

 

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Your Third Brain

Your Third Brain

Here is the link to your PDF copy. Your Third Brain The Revolutionary Discovery to Achieve Optimum Health

Hi, this is Mimi from Bravo Coop sending you a PDF copy of Dr. Ruggiero’s book and my notes.  I hope you enjoy it.  Please feel free to stop by the Bravocoop Teleconference on Tuesday nights to learn more about Bravo Products.    Tuesdays 6:30 PM EST to 8:30 PM EST. Dial into 1-302-202-1106 Then enter Conf Code: 466134

See us, get more info and purchase products  at our website www.bravocoop.com

🙂
Mimi

Pearls from the Your Third Brain: The Revolutionary Discovery to Achieve Optimum Health

  1. The key difference in survival (cancer) is nutrition and the immune system.  Pg 38. In the US and Europe, most people are malnourished Malnutrition is described as the improper balance of three out of four macronutrients: carbs, sugars, proteins, lipids
  2. Microbial strains may hold the key to who we are.  Pg 150 Different microbial strains give us different behaviors aspects such as courage or honesty. You can positively influence your behavior by discovering microbes that give you qualities.
  3. You are what you eat is no joke! Page 151. Food is essentially genetic information which our genes interpret and pass on.  We will suffer if our food is genetic info that is corrupted or incomplete (depleted)
  4. The team worked for months on this premise: Pg217 The most negatively charged molecule in the organic universe was associated with the hydrophobic liquids. Just as if oil and water could uniformly and spontaneously mix.
  5. Then the team worked for years on this premise: (also a paradigm shift) Pg 218-9. That heparin actually directly inhibited the proliferation of cancer cells in vitro (does not imply a “cure”). Heprin seems to perform a novel type of anticancer surveillance on our bodies and then internalized from cell wall.  This info was not accepted prior to their work.  Binding of heparin disturbed the function of DNA of cancer cells in such a way that they couldn’t replicate.  Vitamin D, more like a hormone, than a vitamin was studied.
  6. More secrets revealed Pg 223 Learning about intercellular receptor and Vit D binding protein (Gc) The team showed that the brain is directly connected to the immune system through lymphatic vessels (new science) Pg 229 Autism, Alzheimer, multiple sclerosis to amyotrophic lateral sclerosis are connected to disorders with this connection

This is the practice of using 21st-century medical tech along with boosting the body’s own internal combative systems.  Stimulating the immune system kicks it into high gear and in many cases is able to use that infection to fight cancer.  This kind of boost gives the body something it can fight and it begins to fight all the fights.  

Dr. William Coley was the father of immunotherapy.  He found references from the used 13th century upon which he built his cancer research.  This research went dormant for 50 years.  Dr. Ruggiero revitalized it and much of his work is based upon it.

From Mimi and all of us that are impacted by this work.

Dr. Ruggiero:   Our thanks to you and your team for endless hours of study and keeping yourselves open to the information as it impinges upon you with new revelations.  Then there is the dedication to hold the whole picture and the mechanics on so many levels of how it all fits together. There is also the strength to express it into a world that at times resists change.  To you and your team…  OUR THANKS, SUPPORT, and GRATITUDE!

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The most effective form of exercise isn’t “exercise” at all

The most effective form of exercise isn’t “exercise” at all

By Emmanuel Stamatakis

Have you recently carried heavy shopping bags up a few flights of stairs? Or run the last 100 meters to the station to catch your train? If you have, you may have unknowingly been doing a style of exercise called high-intensity incidental physical activity.

Our paper, published today in the British Journal of Sports Medicine, shows this type of regular, incidental activity that gets you huffing and puffing is likely to produce health benefits, even if you do it in 30-second bursts, spread over the day.

In fact, incorporating more high-intensity activityinto our daily routines—whether that’s by vacuuming the carpet with vigor or walking uphill to buy your lunch—could be the key to helping all of us get some high quality exercise each day. And that includes people who are overweight and unfit.

What is high-intensity exercise?

Until recently, most health authoritiesprescribed activity lasting for at least 10 continuous minutes, although there was no credible scientific evidence behind this.

This recommendation was recently refuted by the 2018 US Physical Activity Guidelines Advisory Report. The new guidelines state any movement matters for health, no matter how long it lasts.

This appreciation for short episodes of physical activity aligns with the core principles of high-intensity interval training(HIIT). HIIT is a hugely popular regimen involving repeated short sessions, from six seconds to four minutes, with rests from 30 seconds to four minutes in between.

Among a range of different regimens, we consistently see that any type of high-intensity interval training, irrespective of the number of repetitions, boosts fitness rapidly,and improves cardiovascular health and fitness.

That’s because when we regularly repeat even short bursts of strenuous exercise, we instruct our bodies to adapt (in other words, to get fitter) so we’re able to respond better to the physical demands of life (or the next time we exercise strenuously).

The same principle is at play with incidental physical activities. Even brief sessions of 20 seconds of stair-climbing (60 steps) repeated three times a day on three days per week over six weeks can lead to measurable improvementsin cardiorespiratory fitness. This type of fitness indicates how well the lungs, heart, and circulatory systems are working, and the higher it is the lower the risk for future heart disease is.

In fact, research suggestsphysical activity intensity may be more important for the long-term health of middle-aged and older peoplethan total duration.

Achievable for everyone

The main reasons people don’t do enough exercise tend to include the cost, lack of time, skills, and motivation.

Exercise regimens like high-intensity interval training are safe and effective ways to boost fitness, but they’re often impractical. People with chronic conditions and most middle aged and older people, for example, will likely require supervision by a fitness professional.

Aside from the practicalities, some people may find back-to-back bouts of very high exertion overwhelming and unpleasant.

But there are plenty of free and accessible ways to incorporate incidental physical activity into our routines, including:

  • Replacing short car trips with fast walking, or cycling if it’s safe;
  • Walking up the stairs at a fast pace instead of using the elevator;
  • Leaving the car at the edge of the shopping center parking lot and carrying the shopping for 300 ft;
  • Doing three or four “walking sprints” during longer stretches of walking by stepping up your pacefor 300-600 ft (until you feel your heart rate is increasing and you find yourself out of breath to the point that you find it hard to speak);
  • Vigorous walking at a pace of about 130-140 steps per minute;
  • Looking for opportunities to walk uphill;
  • Taking your dog to an off-leash area and jogging for 30-90 seconds alongside the pup.

This type of incidental activity can make it easier to achieve the recommended30 minutes of physical activity a day. It can also help boost fitness and make strenuous activity feel easier—even for those of us who are the least fit.

This article is republished from The Conversationunder a Creative Commons license. Read the original article.

 

 

 

 

 

 

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InLight Medical

 

2/15/19 I started the inLight treatments and loved the way I responded to them.  I had some triggered nerves in my calves from chronic adrenal overload.  I went through the program and it calmed it down.  The literature says it may take some weeks/months for nerve training and then maintenance to keep it in place.  It’s like my own version of PTSD in my life every day.  I believe it’s viral and I will track the viral release as the nerve over-firing down.  The only virus that I know of that can act like that is herpes.

 

 

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