Vitamin C improves effectiveness of Chemo Radiation

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The Connection Between Insulin Resistance and the High-Carb, Low-Fat Diet

The Connection Between Insulin Resistance and the High-Carb, Low-Fat Diet

April 30, 2017 | 16,399 views
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By Dr. Mercola

Dr. Tim Noakes, a well-respected scientist, researcher, physician and professor at the Division of Exercise Science and Sports Medicine at the University of Cape Town, South Africa, is one of the world’s foremost experts on low-carb diets. In fact, he was instrumental in getting the low-carb diet revolution off the ground.

He’s also an accomplished athlete. As a long-distance endurance runner with 70 marathons under his belt, he had long promoted high-carb diets, himself consuming 400 grams of carbs a day or more when preparing for a race.

Eventually, he discovered this wasn’t the best way to improve athletic endurance and health, and ended up writing a number of popular books on low-carb diets.

From High to Low Carb

Noakes graduated from medical school in 1974. At the time, he was also running, and this was when the high carbohydrate diet really started to become popularized.

Following the advice of one of his professors at the cardiology unit where he worked, he changed to a high-carb diet and began promoting it in his writings, including the book, “Lore of Running,” which was widely read.

“There it says that you must eat lots of carbohydrates for both health and performance. I continued to do this for 33 years until 2010,” Noakes says.

One day in 2010, he went for a run and had one of the worst runs of his life. He also admitted he was overweight, which didn’t help. By chance, that same day he received an advertisement for Dr. Eric C. Westman’s book, “The New Atkins for a New You: The Ultimate Diet for Shedding Weight and Feeling Great.”

It claimed you could lose 6 kilos (13 pounds) in six weeks, which he didn’t believe because he’d tried many diets and none worked. Despite that, he bought the book, and within two hours of reading, he realized he’d had it all wrong all this time.

“I decided then and there that I was going to go low-carb. I started at lunchtime on that day. I’ve been on that diet now for the last six years. I’ve dropped 20 kilograms (44 pounds) in weight. My running returned to what it had been 20 years earlier,” he says.

“I subsequently discovered that I have type 2 diabetes because of a strong family history and all these carbohydrates. But I’m glad to say today all my blood tests are within the normal range. I am taking medication. But … in six years with diagnosed diabetes, I have not worsened.

In fact, I’m probably slightly better than I was six years ago, which is completely contrary to what would happen if you followed conventional advice. Anyway, I decided that I’d start reading. I read all your work. I read all the books. I started doing research.

That convinced me that this is a really important change that we need to promote throughout the world. Clearly, the diabetes and obesity epidemics started in 1977. It’s caused by the dietary guidelines. I slowly began to understand [how] industry has driven the bad guidelines …

I also do intermittent fasting. I only eat between lunchtime and … 8 p.m. … I found that that’s been really helpful. It’s about a 16-hour fast and an eight-hour period where I eat.”

Diet Revolution Leads to Legal Wrangling

In 2013, Noakes published “The Real Meal Revolution: Changing the World, One Meal at a Time,” which turned into the best-selling book ever in the history of Southern African literature. The success of this book produced major changes in dietary understanding in Southern Africa.

Alas, its success also led to legal action being taken against him by the Health Professions Council of South Africa, which is a professional medical licensing and regulatory board. The action came after he posted low-carb advice to a pregnant woman on Twitter.

As a result, the president of the Association for Dietetics in South Africa wrote a long letter to the Health Professions Council, challenging his ability to practice medicine.

“It is so bad that my own university dissociated itself from me,” Noakes says. “At my hospital, Groote Schuur Hospital, you are not allowed to prescribe a low-carbohydrate diet for any condition. You’re not allowed to discuss the diet among the doctors.

If you do practice it or if you were to prescribe it, something would happen to you. That’s how strong the movement against it is. It’s absolutely astonishing. The worst bit for me actually wasn’t the trial and being accused of malpractice and so on. The worst bit was my university.

The dean of medicine wrote to the local newspaper and said they dissociated themselves from my views and all those who support the low-carbohydrate diet.

Of course, they had no evidence for it, but here I’d worked at this university for 35 years or so, and was one of the better-known scientists. That they could do that was absolutely astonishing. But … it does seem that industry was strongly involved.”

Overwhelming Evidence

During the hearing, he presented five and a half days of testimony about the low-carb diet. He was also cross-examined for three and a half days. Then for another three days, expert witnesses were heard, including Nina Teicholz, Zoe Harcombe and Caryn Zinn, all three of whom presented a remarkably sturdy case for its use.

“For example, when Nina — [who] wrote the book ‘The Big Fat Surprise: Why Butter, Meat and Cheese Belong in a Healthy Diet’ — when she finished, the lawyer for the prosecution could not cross-examine her.

He just threw up his hands and quit. He didn’t have anything to say. Zoe Harcombe was the same. She has just completed her Ph.D., showing there was never any proven evidence to change the dietary guidelines in 1977.

She presented her Ph.D. thesis. Again, the evidence is absolutely overwhelming. The end result is that we’ve had 23 days in court so far, and we won every single moment for 23 days.

We won everything. They have not been able to pin one thing on me. I think it’s the first time in history that a diet has been put before a legal jury to decide whether or not it’s true.”

The final decision, more than three years after the Tweet was posted, was that Noakes was found not guilty of misconduct.

It remains to be seen whether the health professional council, the statutory party that took action against Noakes, will have to change their nutritional guidelines and update all nutrition and dietetics teaching in South Africa. As noted by Noakes, “That could be a huge moment for South Africa and perhaps for the rest of the world.”

Corporate Influence

At the request of CrossFit founder Greg Glassman, investigative journalist Russ Greene visited Noakes in South Africa. He went through all the transcripts of the trial, and then began digging into the backgrounds of all the expert witnesses testifying against Noakes. Most of them turned out to be linked to an organization called the International Life Sciences Institute (ILSI), which is a Coca-Cola funded organization.

ILSI is basically a front-group for the beverage industry, and has links to Monsanto, Pfizer, Unilever and, in the past, the tobacco industry. Green wrote an exposé, “Big Food vs. Tim Noakes: The Final Crusade,” which is posted on his website, therussels.crossfit.com.1

“It’s an amazing exposé, which suggests there was a coordinated effort in South Africa to bring me [down] and that it was driven by industry. The reason was we were getting too close to questioning the role of sugar and carbohydrates in ill health. We haven’t proved it, but there’s enough evidence out there to suggest there were things behind the trial that one would not have thought about,” Noakes says.

Beverage Industry Hurt Athletes With Manipulated Science

This isn’t the first time Noakes has taken on big industry. In 2010, he published “Waterlogged: The Serious Problem of Overhydration in Endurance Sports,” a book exposing how industry influences science, and how the beverage industry has influenced the drinking guidelines for athletes.

He wrote the book because he was angry about people being hurt as a result of these manipulated guidelines. While rarely discussed, exercise-associated hyponatremia — drinking too much or overhydrating — actually contributes to many unnecessary deaths. Noakes explains:

“When I started running marathons in the 1970s, we didn’t drink during races. In fact, I ran a 56-mile race and I think I had four drinks. You’d have a drink every hour and you would literally swirl your mouth out with water and that would be about it. No one came to any harm. Then in about 1974 I began actively to promote drinking during marathon races. I became very active in South Africa saying there was not enough fluid available to marathon runners …

By 1981, the race … had a drinking station every mile. They had 56 drinking stations in a 56-mile race. At the end of that race, a lady was unconscious. She was hospitalized … Her blood sodium concentration had fallen. She wanted to know what had happened. She said, ‘Maybe I took too little sugar or salt during the race. What should I do about it?’ I said, ‘I have no idea.’

I then decided to investigate. Over the next 10 years, we were able to show that … she had overdrunk fluids. She’d retained the fluids, [which] caused her brain to swell, [causing] her to go unconscious. She’d remained unconscious for four days. We provided definitive evidence that it was overdrinking that caused the problem.”

In 1993, the first American marathon runner died from overhydration. Still, in 1996, the American College of Sports Medicine, funded by Gatorade, produced new drinking guidelines stating that dehydration is the killer when you exercise, and you should drink “as much as tolerable” during exercise.

Other deaths followed, all of which were completely unnecessary. In 2002, a young female runner died shortly after completing the Boston marathon. Cause of death: water intoxication. As recently as last year, two American football players died from overhydration. An estimated 3,000 athletes have also been hospitalized for hyponatremia, but fortunately almost all have survived. Yet, there have been at least 16 completely unnecessary deaths of which we are aware.

How Industry Controls Information

Finally, in 2007, the American College of Sports Medicine revised their guidelines to what Noakes had suggested, which is that you should drink to thirst.

“It took a lot of time to change. The only reason we could change was because two scientific journals in the entire world were independent of the sports drink industry. [The] industry … makes sure its key opinion leaders, who have funds to do research, also happen to be the people who draw up the guidelines, whether they be dietary, cholesterol or drinking. In addition to that they are the main reviewers of journal articles.

Over a 10-year period, we would submit papers and I knew they went to exactly the same reviewers every time. It didn’t matter which journal we sent them to … But there were two journals that were independent, the British Journal of Medicine and the Clinical Journal of Sports Medicine. They published our work. I always knew that if there were two journals open to our papers … we would win in the end. In the end, we did win, because in the end all that matters is the truth.

But if those two journals had also been controlled, if they’d had the same editorial boards, we wouldn’t have ever done it. That was how I learned that is how industry controls information. They actively do it. They actively support people to make sure that only guidelines that benefit industry are ever published.”

With Fewer Carbs, You Don’t Need Insulin

One of the absolute worst things conventional medicine does is treat type 2 diabetics with insulin. This only exacerbates the problem. The key to treating and reversing type 2 diabetes is to cut down on net carbs, replacing them with high amounts of healthy fats and moderate amounts of protein. Noakes has researched reversal of type 2 diabetes in South Africans, coming to the same conclusion.

“It seems to me that provided you remove the carbohydrates, you don’t need the insulin,” he says. “We’re looking at the whole body … [W]e’re looking at every organ in the body that we believe has been influenced by type 2 diabetes.

We’re seeing how they differ in people who reversed their type 2 diabetes on this diet, versus those who continue to be treated with standard therapy, including insulin … [This has] not been done anywhere else in the world. It’s just the most exciting work I can think of.”

Removing net carbs is only one side of the equation, though. That will reverse the insulin resistance, but equally important is having the ability to burn fat as your primary fuel. Paradoxically, driving your insulin level too low can result in a rise in blood sugar. The reason this can happen is because the primary function of insulin is not to drive sugar into the cell, but to suppress the production of glucose by the liver (hepatic gluconeogenesis).

In situations like this, eating a piece of fruit, for example, will actually lower your blood sugar. This is what happened to me, as I went a bit too extreme in my ketogenic approach. That got me to explore this whole process, eventually concluding that continuous ketosis may not be a wise long-term approach.

You actually need this cycling, where you go through a one-day-per-week fast and one or two days a week of feasting, where you eat maybe 100 or 200 grams of carbs. Noakes is planning clinical trials with type 2 diabetics where they will be looking at these kinds of variations.

Are Carbs Bad for All Athletes?

It’s worth noting that some athletes may not perform at their best on a ketogenic (high-fat, low-carb diet). I believe that if you’re doing ultra-endurance events like marathons, the ketogenic diet is the way to go. But for high-performance spurt, interval types, it might not be your best bet. It’ll help you from a health perspective, but it may not optimize your performance like it will for long-distance running. Noakes weighs in on the topic, saying:

“I say the ideal diet for sports is the one that’s ideal for life as well … I spent 20 years of my life studying glucose metabolism in the body during exercise. The question I want to know is, how can adding a little bit of carbohydrate make you run faster? For example, if you ingest carbohydrate during exercise, because you’ve got plenty of fat on board, why would you need a little bit of carbohydrate?

To some extent, I think the carbohydrate effect is a drug effect, particularly during exercise. If you’re taking carbohydrates, I think it’s acting like a drug, because metabolically, I can’t see how it would make any difference. It’s really interesting.

When we do these studies, we take people on high-carbohydrate diets and we put them on a high-fat diet. The performance does come down. But I wonder to what extent, as to the withdrawal of the drug effect as much as a metabolic effect … I think even if you’re cycling the Tour de France, you don’t need more than 200 grams of carbohydrate a day.”

Insulin Resistance Is the Real Killer

According to Noakes, “[I]nsulin resistance is the real killer and … we need to understand that … [the] main driver [of chronic disease] is insulin resistance and a high-carbohydrate diet.”

Unfortunately, most medical schools around the world still do not teach medical students about insulin resistance, and one of the primary reasons for this is because medical schools are strongly influenced by the food industry, which wants you to believe that eating fat is dangerous and eating sugars and grains (net carbs) is healthy.

Neither is true, but these ideas are driven by financial motives. We need to remember that diabetes is one of the greatest growth industries in the world. If it can be reversed or prevented by a relatively simple dietary change, then that industry collapses.

“What I would like to dedicate the rest of my time to is trying to get medical schools to change the focus of the teaching of nutrition and to admit that we failed by telling people to eat a high-carbohydrate diet, and that we have to replace that with an understanding that carbohydrates and insulin resistance are the problem. The broad range of diseases that we see is linked to that,” Noakes says.

“There’s a paper in the Journal of American Medical Association … Chinese people with diabetes were compared to Chinese people without diabetes. The risk for all the common chronic diseases was two to three times greater. It was frightening. There wasn’t a condition that wasn’t listed there.

We have to realize we’re heading toward a disaster because we don’t understand that you must treat insulin resistance with a low-carbohydrate diet. Unless we do that, we’re not going to address the health of our nations … We used to be very lean. That’s what we’re designed to be. We have to somehow get back to that original state, because humans are … not designed to be fat.”

Sugar Addicts Are Particularly Intolerant to Carbohydrates

While I believe limiting protein is just as important as cutting carbs, Noakes believes restricting carbs is the primary key for diabetics. As for how much carbohydrate is too much, we agree that an ideal limit for health is 25 grams of net carbs per day. My recommendation for diabetics is stricter than his, however, as I recommend a maximum of 15 grams of net carbs per day until your insulin resistance is resolved.

Noakes suggests a range of 25 to 100 grams, depending on your levels of exercise and of insulin resistance, with 25 grams being the maximum for those with marked insulin resistance/Type 2 diabetes. He also notes that people with sugar addiction or carbohydrate addiction who are morbidly obese tend to be incredibly intolerant to carbohydrates, and need to be particularly mindful not to exceed 25 grams of net carbs.

“The people that I’ve helped lose 80, 100 kilograms, that’s 160 to 200 pounds, they literally cannot eat 26 grams of carbohydrates. They have to stick to 25. Once they get up to 50 grams … they move back toward the addictive nature,” Noakes says.

“They start to eat more carbohydrate, and very quickly, they’re eating 100, 200, back to 400 grams. People don’t understand that if you have a real weight problem and you’re morbidly obese, you’ve really got to be strict 25 grams and no more. I think it’s the same with type 2 diabetes. You’ve got to stick to 25 grams.”

Dr. Noakes was one of the experts I sought to help edit my new book “Fat for Fuel” for accuracy. Unfortunately, he was in the middle of his trial and could not edit it. However, there is little doubt in my mind that “Fat for Fuel” is the finest resource you can obtain to give you the practical details of how to implement the strategies that Noakes discusses.

To Learn More, Join Me at My Upcoming Live Lectures

There are many professionals or others who would like to dive deep into the details and if you fall in that category, I want to offer you some opportunities to learn more. On June 14 and 15, 2017, I will be in Colorado Springs for the SopMed’s third medical ozone and ultraviolet light therapy training. The 14th I will be giving a three-hour course that goes into many of the details that are not discussed in my new book “Fat for Fuel,” either because I learned of them later or there was not room to fit them in the book.

If you are specifically interested in nutritional ketosis, there will be a large number of experts lecturing at the Low Carb USA event in San Diego August 3-6. I will be one of the speakers along with Gary Taubes and Stephen Phinney. You can see the entire list of invited speakers lower on the page. The Early Bird Special, which saves you $100 on the ticket price, ends on April 30.

I am also speaking in Florida in November. If you are a physician and are interested in learning about how you can use the ketogenic diet and other therapies for cancer, heart disease, Lyme and neurodegenerative diseases like Alzheimer’s and Parkinson’s, please be sure and come to our ACIM conference in Orlando, Florida on November 2 through 4 at the wonderful Florida Conference and Hotel Center.

If you are a patient, there will be a separate and less expensive track on the same date and location.  However, you will need to come back to this page in a few days as the registration page for the event is still not up. The Early Bird Special, which saves you $100 on the ticket price, ends on April 30.

 

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Lobelia May Help in Respiratory Health and Muscle Relaxation

http://articles.mercola.com/herbs-spices/lobelia.aspx?utm_source=dnl&utm_medium=email&utm_content=secon&utm_campaign=20170424Z1_UCM&et_cid=DM141335&et_rid=1980243242

 

Lobelia (Lobelia inflata), or Indian tobacco, is a flowering herb that is named after the Belgian botanist, Matthias de l’Obel.1 It was formerly used as a substance during smoking cessation, but has since been discontinued because of mixed results.

In a broader sense, lobelia can refer to a wide variety of flowering plants, with some botanists claiming that these varieties belong to a separate family, Lobeliaceae.2 One of the most common and popular variety of lobelias is the Lobelia inflata variety.

Other varieties of lobelia plants include both Lobelia siphilitica and Lobelia cardinalis. These varieties can normally be distinguished from the Lobelia inflata through the differences in the color of their flowers.

Lobelia siphilitica is the most cultivated variety of this plant and is often called the “great blue lobelia” because of its vivid blue flowers, as opposed to the pale color of Lobelia inflata.3 Lobelia cardinalis is also much easier to differentiate because of the distinct bright red color of its flowers.4

Because of its dainty flowers, lobelia plants are usually planted in the garden or window boxes to visually improve people’s surroundings. However, because of its beauty, its nutritional components are typically overlooked.

Nutritional Benefits of Lobelia Inflata

Here are some of the benefits that you’ll likely receive when you start using lobelia therapeutically:5

Respiratory stimulant and antispasmodic. Lobelia functions as a bronchodilator, meaning it stimulates the respiratory system and may even help in alleviating the effects of asthma. It may also help relax the lungs when they’re tense or overworked.

Expectorant. It triggers the secretion of sputum through the air passages, which is why lobelia is commonly used to ease asthma and bronchitis.

Diaphoretic. As a diaphoretic, lobelia promotes perspiration, which helps in cooling the skin during the onset of fever.

It also aids in eliminating toxins from the body and promoting healthy blood circulation.6 Diaphoretics are often used to relieve diarrhea, kidney and liver conditions.7

Muscle relaxant. Lobelia has a depressant property, which helps the autonomic nervous system and muscular system relax.

How Do You Use Lobelia?

There are various ways in which lobelia can be used. The tincture of the herb can be usedto help alleviate sprains, bruises and various skin conditions. A poultice can also be used topically and may help relax your muscles, especially smooth ones.8

Listed below are the various forms that lobelia is available in along with the recommended intake dosages:9

Dosage

Powdered bark: 5 to 60 grains

Fluid extract: 10 to 20 drops

Acid tincture: 4 to 15 milliliters

Tincture: 4 to 15 milliliters

Syrup: 4 to 15 milliliters

Solid extract: 4 to 15 milliliters

It should be noted that these are only recommended doses and an individual’s tolerance level for this herb may vary. Consult your physician to determine the appropriate dosage for you, so that you can avoid ingesting too little or too much of this herb.

Here’s How You Can Grow Your Own Lobelia

Lobelia is commonly planted in regions with low temperatures. But while they thrive well in cold climates, they are actually very sensitive to frost. Listed below is a step-by-step guide on how to successfully plant lobelia in your backyard either for ornamental or medicinal purposes:10

1. Start indoors roughly 10 to 12 weeks prior to the last frost in your region. Spread the tiny seeds just on top of the soil and water thoroughly. Place them in a warm, well-lit area.

2. The seedlings should pop up within a week or two, at which time you can begin thinning them out.

3. After the danger of frost is gone and the plants are at least 2 to 3 inches tall, transplant them to your garden — spacing them about 4 to 6 inches apart.

4. During hot and dry periods, water the plants frequently, especially if they are planted in containers.

Try This Recipe for This Muscle Relaxer Tea

Because of the strong effects of lobelia when taken in its pure form, some people choose to incorporate it into their various tea recipes. One such example is a recipe from Living Herbal Tea that combines lobelia with other tea leaves:11

Muscle Relaxer Herbal Tea Recipe

Ingredients:

  • 2 tablespoons of sage
  • 2 tablespoons of chamomile
  • 1 tablespoons of peppermint
  • 1 pinch of lobelia
  • Water

Procedure:

1. Combine herbs. Steep 1 tablespoon of the herb blend in 8 ounces (approx. 1 standard mug full) of boiled water for 5 to 7 minutes. Steeping too long or too hot will cause bitterness in the blend.

2. Keep your cup covered while the tea steeps to make sure you don’t lose any of the amazing flavor or healing properties.

3. Allow the tea to cool to a safe and comfortable temperature. Sip and enjoy.

Watch Out For These Contraindications and Possible Side Effects of This Herb

Lobelia, even though it has a variety of health benefits when taken in moderation, may actually be poisonous when ingested in large quantities. It’s also poisonous for pets and other animals, and should be removed from the vicinity where these pets reside to avoid them from being harmed.12 Some of the side effects that you may experience when you ingest lobelia include the following:13

Profuse sweating

Nausea and vomiting

Diarrhea

Heart palpitations

Disorientation

Lobelia should also be avoided if you suffer from the following conditions and diseases:

High blood pressure and heart disease. Lobelia is a vasomotor stimulant and may cause an increase in blood pressure. This may worsen the symptoms of high blood pressure and may cause irreversible damage.14

Tobacco sensitivity. Lobelia contains lobeline, a substance that has the same effect of nicotine in the human body. This may mimic the negative effect of nicotine on people with tobacco sensitivity.15

Lobelia should also be avoided by people who suffer from liver or kidney disease, seizures and shortness of breath. Like other herbs and medications, the use of lobelia should also be avoided by pregnant and breastfeeding women, as it may cause adverse effects.16

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Lower High Blood Pressure With More Potassium-Rich Foods, Less Sugar

http://articles.mercola.com/sites/articles/archive/2017/04/24/potassium-rich-foods-lower-blood-pressure.aspx

By Dr. Mercola

Americans struggle with high levels of certain diseases like cardiovascular disease and related high blood pressure. In fact, the World Health Organization ranks this malady, also known as hypertension, as playing the leading role in heart disease.1

Conventional medicine says eating too much sodium is one cause of high blood pressure, but more studies are revealing that it’s actually an imbalance between your sodium intake and your potassium levels that may be the problem. According to one study:

“Findings suggest that public health efforts directed toward increasing consumption of K+ [potassium]-rich natural foods would reduce BP [blood pressure]and, thus, cardiovascular and kidney disease.”2

Potassium deficiency, known as hypokalemia, can be so serious that it could be fatal. One sign that you may be deficient is high blood pressure, but other things to look for include:

  • Fatigue
  • Muscle weakness
  • Abdominal pain and cramps
  • Abnormal heart rhythms
  • Muscle paralysis

Potassium: The ‘Good Salt’

There are a few facts about potassium that few people are aware of. First, it’s an essential mineral, but another thing to note is that, as an electrolyte, it plays a crucial role in regard to your blood pressure.

In spite of loads of studies and reports to the contrary, the fact is that it’s the balance between salt and potassium that will balance the health of your cells, not lowering your salt intake, unless of course, you’re talking about processed table salt.

Foods With High Potassium Content Help Lower Blood Pressure Levels

People with higher intakes of potassium tend to have lower blood pressure levels, so finding the foods to eat that contain it will definitely be good for you. For a good balance of potassium to sodium in your diet, eat fresh, whole, potassium-rich foods. I recommend:

Swiss chard Avocado Spinach Crimini mushrooms
Broccoli Brussels sprouts Celery Romaine lettuce

A passionate reader asked me to add this to my post about Brussel sprouts. https://www.jenreviews.com/brussels-sprouts/. This is a great and informative post with some science and recipes on Brussels sprouts.  My hubby likes them so we eat them a lot.

Additionally, Authority Nutrition3 notes other foods with high potassium content, such as leafy greens, tomatoes and sweet potatoes, wild-caught Alaskan sockeye salmon, melons, bananas, oranges and apricots. Fruits should be eaten in moderation, however, due to the fructose content.

Besides significantly lowering your blood pressure, pomegranate juice may protect your cells from negative effects like premature aging.

It’s also high in antioxidant polyphenols to cut your cancer and heart disease risks, and more antioxidants from tannins, anthocyanins and ellagic acid than green tea and red wine, Prevent Disease adds.4

Fruit polyphenols have been shown to have such a positive influence on potentially fatal heart-related issues that related research may even help change recommendations on what fruits are most beneficial to consume for optimal cardiovascular protection, one study concluded.5

A Florida study6 reported that 1 cup of blueberries a day may lower blood pressure and relax arteries. Around 50 hypertensive women were given either 22 grams of freeze-dried blueberry powder or a placebo powder to eat, with the result that the first group, on average, had a 7 mmHg drop in systolic blood pressure.

Raw grass fed yogurt is rich in probiotics, which helps keep blood pressure at balanced levels.

A review of several studies7 found that probiotics may benefit this area of your health naturally because they help optimize your cholesterol and lower blood sugar levels. And small amounts of dark chocolate provide flavonoids that cause blood vessels to dilate.8

Lifestyle Changes You Can Make to Lower Your Blood Pressure

Most people will say they want to live a “healthy” life, but it’s usually small, day-to-day decisions that make the difference in the long run. Blood pressure affects your body in a systemic way. If you struggle to maintain healthy levels, you may want to take a good look at your diet.

Conventional wisdom usually tells you to limit your salt intake, but the most impactful way to do the job is to cut down on sugar. As “bad” as salt is touted to be, sugar is far worse.

While you probably already know that processed foods are far too high in refined sodium, it’s refined sugar that’s the real culprit in the high incidence of high blood pressure and, consequently, the trickle-down effect of diseases that all too often follow along behind, such as metabolic syndrome, atherosclerosis, stroke and heart attack.

More and more studies indicate that sugar can be implicated in high blood pressure levels.9 In fact, one study shows that women who drank just one soda per day had higher levels that those who drank less than that.10

Researchers at the University of California–San Francisco and Touro University California conducted a study11 published in the journal Obesity that looked at the effects of limiting sugar intake. The study subjects were 43 children between the ages of 9 and 18 years.

For nine days, all the children ate meals, snacks and beverages with reduced sugar; however, they were allowed to eat fruit. Their fasting blood sugar levels, glucose tolerance and blood pressure were recorded before each meal.

All of them were given the same amounts of protein, fat and carbohydrates as before, including hot dogs, chips and pizza, but added sugar was replaced with bagels and cereal. In fact, sugar went from 28 percent to 10 percent. Carbs and fructose were reduced from 12 percent to 4 percent.

What Happens When Children Are Given Less Sugar to Eat?

Before long, the diet proved successful, as the scientists noted decreased blood pressure, improved cholesterol and improved liver function. Fasting blood glucose levels fell five points, while insulin levels dropped by a third.

This is particularly astonishing since the added sugar was replaced with bagels and cereal, which are far from healthy. Imagine if it had been replaced with vegetables or healthy fats! Lead author Robert Lustig stated:

“This study definitively shows that sugar is metabolically harmful not because of its calories or its effects on weight; rather sugar is metabolically harmful because it’s sugar.

(The study indicates) that sugar contributes to metabolic syndrome, and is the strongest evidence to date that the negative effects of sugar are not because of calories or obesity.”12

The Epoch Times quoted senior study author Jean-Marc Schwarz:

“These findings support the idea that it is essential for parents to evaluate sugar intake and to be mindful of the health effects of what their children are consuming. When we took the sugar out, the kids started responding to their satiety [fullness] cues.

They told us it felt like so much more food, even though they were consuming the same number of calories as before, just with significantly less sugar. Some said we were overwhelming them with food.”13

Active African-Americans Are Less Apt to Develop High Blood Pressure

Certain factors make high blood pressure more prevalent in some people than in others. One study based in Jackson, Mississippi, showed that African-Americans are less apt to develop high blood pressure if they’re physically active on a daily basis.

Further, study subjects who reported engaging in the ideal amounts of moderate to vigorous physical activity were about 24 percent less likely to have high blood pressure years later in comparison to those who didn’t.

As it happens, African-Americans have the highest blood pressure rates of any racial or ethnic group in the U.S., making heart attack, stroke and kidney disease risks more prevalent, and even early death. Unfortunately, the odds are high for this demographic. Dr. Keith Diaz of Columbia University Medical Center in New York explained:

“If you’re African-American, your odds of developing hypertension [are] pretty high. If you’re worried about hypertension or high blood pressure, one of the things you can do to prevent it is physical activity and exercise.”14

None of the 1,311 participants in the study had high blood pressure when they started it between 2000 and 2004. They were checked again between 2005 and 2008, and again between 2009 and 2013. Half them were monitored for at least eight years.

The upshot? Those getting 150 minutes of moderate-intensity exercise per week, or at least 75 minutes of vigorous exercise — specifically from programmed physical activity as opposed to household tasks —  were 24 percent less likely to have developed high blood pressure than people who didn’t.

How to Lower Your Blood Pressure Naturally

Most doctors charged with helping their patients with high blood pressure issues will hand their patients a pharmaceutical prescription, but there are remedies for this condition that cost far less, financially, physically, overall time consumed and long-term effects combined. Time15 and Authority Nutrition listed several, including:

  • Breathe. Mindfully slowing the breaths you take and breathing more slowly helps you relax, and relaxing helps improve your heart rate, makes your arteries more flexible and lowers your blood pressure, naturally.
  • Relax. Stress does more to negatively affect your body than you can imagine. Bouts of anger or stress, triggering your “fight or flight” hormones, can literally increase your risk of developing heart-related issues. Try the Emotional Freedom Techniques (EFT) and other natural methods to calm and soothe your mind.
  • Curb the coffee and alcohol. While there are studies that contend that moderate alcohol intake can provide heart benefits, overdoing it can raise your blood pressure, as well as cause subsequent health problems. Caffeine can also be a culprit, and it may come from drinking soda. Give it a rest — literally.
  • Walk and exercise regularly. Your heart is strengthened and pumps blood more efficiently, lowering arterial pressure. Just 150 minutes of moderate exercise like walking or 75 minutes of strenuous exercise such as high-intensity interval training (HIIT) can improve both.16
  • Lose weight. Even losing 5 percent of your total weight can significantly lower your blood pressure,17 and the effect is even greater when you exercise.18

 

 

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Commentary on two recent papers on GcMAF

 Commentary on two recent papers on GcMAF

Marco Ruggiero, MD, PhD

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Two important papers on GcMAF have been published in the past few days in peer-reviewed journals.

The paper by Borges and Rehder of the School of Molecular Sciences and of the Biodesign Institute at Arizona State University, Tempe, AZ, USA, clari es the chemical structure of the protein moiety of GcMAF, and represents a signifcant improvement in our understanding of the concepts and significance of GcMAF and nagalase. (Glycan structure of Gc Protein-Derived Macrophage Activating Factor as revealed by mass spec- trometry. Borges CR, Rehder DS. Arch Biochem Biophys. 2016 Aug 5. pii: S0003-9861(16)30278-8. doi: 10.1016/j. abb.2016.08.006).

It is interesting to notice that the paper by Borges and Rehder was published almost simultaneously with our latest paper on GcMAF (Medical Hypotheses 94 (2016) 126–131), and, although none of us was aware of each other’s imminent publication, the two papers are fully consistent with each other as they shed a new light on the interpretation of the results that have accumulated over the course of the past twenty years on GcMAF.

It is worth remembering that Borges and Rehder had published another important paper on the subject a few years ago, where they demonstrated that there is no lack of GcMAF precursor in cancer patients, as opposed to the prevailing theory of those days (Protein Sci. 2009 Oct;18(10):2036-42. doi: 10.1002/pro.214. Glycosylation status of vitamin D binding protein in cancer patients. Rehder DS, Nelson RW, Borges CR). Thus, according to the original theory rst proposed by Yamamoto, nagalase would “destroy” the precursor of Gc- MAF and, therefore, cancer patients would be unable to produce endogenous GcMAF: because of this, Gc- MAF had to be administered from the outside (Immunotherapy for Prostate Cancer with Gc Protein-Derived Macrophage-Activating Factor, GcMAF. Yamamoto N, Suyama H, Yamamoto N. Transl Oncol. 2008 Jul;1(2):65– 72).

Borges et al. demonstrated that this was not the case and cancer patients have plenty of their own GcMAF.

In the study of 2009 Borges et al. wrote: “The presence of relatively abundant quantities (5–10 mg/L or 100–200 nM) of what might nominally be considered GcMAF (i.e., DBP modi ed by a single terminal Gal- NAc residue) in cancer patient serum … present a paradox in which cancer patients with relatively high cir- culating concentrations of GcMAF can effectively be treated with trace quantities of (exogenous) GcMAF”.

This observation seems to indicate that there is no shortage of endogenous GcMAF production in cancer patients and, therefore, that GcMAF is not responsible for “protection” against the development of cancer.

Such a concept is further corroborated by the study of the cancer risk in individuals harboring the Gc2 alle- le only (Gc2 homozygotes) of the Gc protein. These individuals are unable to glycosylate the Gc protein on threonine 420 due to its substitution by lysine.

Thus, there is no N-acetylgalactosamine (GalNAc) in position 420. In other words, Gc2 homozygotes are unable to produce one single molecule of GcMAF but, despite this fact, the risk of cancer in these individu- als is decreased rather than increased as one would have expected given the absence of bona de GcMAF (Abbas S, Linseisen J, Slanger T, et al.: The Gc2 allele of the vitamin D binding protein is associated with a decrea- sed postmenopausal breast cancer risk, independent of the vitamin D status. Cancer Epidemiol Biomarkers Prev, 2008, 17: 1339-1343.). It should be noticed that this inconsistency refers to breast cancer that is one of the types of cancer where GcMAF had proven effective in vitro, and in vivo.

In the paper published a few days ago, Borges and Rehder further confirm these observations using carefully designed mass spectrometry methods, and highlight two important points that lend credit to our most recent hypothesis on the nature of GcMAF (Medical Hypotheses 94 (2016) 126–131).

  1. Nagalase does not affect the Gc protein, that is the precursor of GcMAF and, therefore, elevated nagalase levels do not correspond to reduced production of GcMAF. At variance with previous assumptions, Borges and Rehder demonstrate that nagalase is not endowed with endo-glycosi- dase activity and, therefore, cannot degrade the Gc protein. This carefully conducted observation explains the reason why cancer patients have elevated levels of endogenous GcMAF despite elevate serum nagalase activity.
  2. Beta-galactosidase, one of the enzymes used to (theoretically) convert the inactive Gc-protein into the active GcMAF by removing the galactose from the threonine 420 and exposing the GalNAc, does not work on the Gc-protein and does not remove the galactose; this means that the procedures to produce GcMAF by removal of galactose using beta-gaalcotsidase are, in actuality, ineffective. According to this observation, enzymatic treatment of purified Gc protein, or of serum, does not yield GcMAF but only a desialidated Gc protein where the GalNAc is still “covered” by galactose. According to the original theory proposed by Yamamoto, such a Gc protein with galactose still attached to GalNAc should be devoid of macrophage stimulating activity.

The results published a few days ago by Borges and Rehder are fully consistent with those published in 2010 by a Danish group using mass spectrometry, demonstrating that the three sugars on the Gc protein are arranged in a linear fashion (threonine 420-GalNAc-galactose-sialic acid) and, therefore, beta-galac- tosidase cannot work since it is not endowed with endo-glycosidase activity (Biochim Biophys Acta. 2010 Apr;1804(4):909-17. doi: 10.1016/j.bbapap.2009.12.022. Epub 2010 Jan 13. The glycosylation and characteriz- ation of the candidate Gc macrophage activating factor. Ravnsborg T1, Olsen DT, Thysen AH, Christiansen M, Houen G, Højrup P).

The lack of effect of the beta-galactosidase also forces to reconsider the interpretation of the results reported by the researchers from the University of Tokushima and from the Saisei Mirai Clinic of Japan, who demonstrated anti-cancer effects obtained by treating the Gc protein only with beta-galactosidase (Anti- tumor effect of degalactosylated gc-globulin on orthotopic grafted lung cancer in mice. Hirota K, Nakagawa Y, Takeuchi R, Uto Y, Hori H, Onizuka S, Terada H. Anticancer Res. 2013 Jul;33(7):2911-5. β-Galactosidase treatment is a common rst-stage modi cation of the three major subtypes of Gc protein to GcMAF. Uto Y, Yamamoto S, Mukai H, Ishiyama N, Takeuchi R, Nakagawa Y, Hirota K, Terada H, Onizuka S, Hori H. Anticancer Res. 2012 Jun;32(6):2359-64).

Quite obviously, treatment with beta-galactosidase alone did not produce any bona de GcMAF and, therefore, the observed anti-cancer effects have to be ascribed to some other mechanism or some other molecules.

The two most recent papers published on GcMAF may thus help reconcile several contradicting observations that have accumulated over the years. Such inconsistencies and contradictions are:

  1. The procedure to produce GcMAF using enzymatic treatment of purified Gc protein or serum using beta-galactosidase does not produce one single molecule of bona de GcMAF.
  2. Cancer patients who were successfully treated with what was thought to be GcMAF, but in actuality was not, had plenty of their own GcMAF, a quantity that was far higher than the trace amounts of the desialidated Gc-protein that was administered thinking it was GcMAF. Although the levels of GcMAF in autistic patients has never been determined, the inability of nagalase to reduce the production of GcMAF leads to conclude that also autistic children with elevated nagalase had normal level of endogenous GcMAF. Nevertherless they were successfully treated with desialidated Gc-protein that was administered thinking it was GcMAF.
  3. These inconsistencies notwithstanding, it is a fact that “GcMAF” (between quotation marks since now we know that it was not bona de GcMAF) has proven effective in vitro and in vivo, and the laboratory and clinical data obtained with “GcMAF” have been repeatedly and independently confirmed.

These contradictions and inconsistencies may all be solved if we consider the hypothesis put forward our most recent paper in Medical Hypotheses; a hypothesis that reconciles the apparently contradicting observations quoted above. In other words, we do not dispute the validity of any of results of the papers thus far published on GcMAF; in our opinion, it is their interpretation that needs to be revisited at the light of the most recent publications.

Our concept, that has been defined by Borges as “interesting and plausible” at the light of their own most recent results, is that the Gc protein, whether with one, two or three sugars, or with any sugar moiety as in the case of the Gc2 homozygotes, plays a little role, if any, in the activation of macrophages or in any of the other biological and clinical effects that we and others have described for what we thought was “GcMAF”. According to our hypothesis, it is a glycosaminoglycan that binds to the Gc protein, chondroitin sulfate, in conjunction with vitamin D and oleic acid bound to the Gc protein, that is responsible for the effects attributed to the “GcMAF”. The Gc protein, deglycosylated or not, at most is a carrier for chondroitin sulfate, vitamin D and oleic acid.

Our new interpretation also explains the well acknowledged fact that treatment with “GcMAF” leads to reduction of nagalase levels in patients with different diseases, and leads to reconsider the role of nagalase as a marker.

Thus, nagalase cannot be considered a marker of immunodeficiency since its elevated levels do not correspond to decreased levels of endogenous GcMAF and, more importantly, elevated levels of nagalase have never been associated with any deficiency of the immune system. For example, autistic subjects have levels of nagalase higher than those of many cancer patients and nevertheless they are not immune deficient in the least.

However, nagalase seems to be a very reliable marker of chronic inflammation regardless of the causes that are responsible for in ammation (J Proteome Res. 2015 Aug 7;14(8):3123-35). This would explain the reason why nagalase is elevated in diseases that have nothing in common but chronic inflammation such as cancer and autism.

In the case of cancer, it is of particular importance to notice that in ammation in itself plays a major role in the progression of the disease and it is, in and by itself, a predictor of negative prognosis as we have de- monstrated in 2012 (Fabris et al. American Journal of Immunology, 2012, 8 (3), 65-70).

If we consider that the biological and clinical effects that had been attributed to GcMAF are indeed to be ascribed to a multimolecular complex made of chondroitin sulfate, vitamin D and oleic acid, with the Gc protein playing a minor role if any, then it makes full sense these three molecules decrease nagalase, since they are very well known to have anti-inflammatory properties. It is also worth mentioning that chondroitin sulfate, vitamin D and oleic acid also show immune-stimulatory, anticancer and neuroprotective pro- perties that are superimposable to the biological and clinical properties thus far attributed to GcMAF.

Therefore, nagalase could be interpreted as a marker of chronic inflammation and evaluation of serum nagalase levels could be useful in monitoring the effectiveness of immunotherapies regardless of the under- lying disease. In this respect, nagalase measurement would have an advantage over specific markers such as tumor markers, since its variations would be useful in a much broader range of conditions.

In conclusion, the almost simultaneous publication of the papers by Borges and Rehder and by our research group opens a completely new perspective in the field of immunotherapy and GcMAF research, and helps solving the inconsistencies and contradictions that have characterized this field in the recent past.

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Friedrich-Luber-Straße 29 Tel. +49 (0)9128 73977-0 Mail shop@drreinwald.com DE 90592 Schwarzenbruck, Germany Fax +49 (0)9128 73977-29 Web www.drreinwald.com

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BravoCoop seeks to establish a Private Membership Association

Private Membership Association

Home Private Membership Association

1st and 14th Amendment Private Medical Association for Unlicensed or Licensed Medical Practitioners

In reviewing medical email solicitations, newsletters and other medical publications over the years, we at ProAdvocate Group are more than ever convinced than ever that there are numerous proven therapies/treatments outside of mainstream medicine that are providing relief and/or  cures for a wide variety of afflictions and diseases.

Unfortunately, there are untold numbers of alternative healthcare practitioners — I am sure you know several—who possess these therapies and treatments but are unable to effectively advertise, market, and practice their craft in the public domain because of the heavy hand of state or federal boards, regulators, law enforcement agencies and others who police any public unlicensed medical practice. 

What are the Benefits of a 1st and 14th Amendment Private Medical Membership for Unlicensed or Licensed Medical Practitioners?

  1. Eliminate Illegal Investigations and Sanctions by any Licensing Board.
  2. Practice Medicine in your chosen area without paying outrageous malpractice insurance premiums – LESS RISK OF MALPRACTICE LAWSUITS AND CLAIMS.
  3. Practice Medicine without the burden of strict compliance with the Federal Laws dealing with the protection of the public and HIPPA Laws.
  4. Maintain privacy of business and financial affairs.
  5. Practice alternative medical modalities without fear of discrimination and sanctions.

And most of all ……..

  1. Maintain more freedom and control of your chosen profession.

This letter is to inform you that there are real solutions to your present and future potential problems in practicing alternative medicine and ProAdvocate Group can be part of that solution. As you know, many of your fellow practitioners are being harassed, investigated and sanctioned by medical boards, law enforcement agencies and attorney generals in many states. They, of course, believe a great service is being performed in the name of “protection of the public.”

The solution to the problem is to change the public patient or client relationship into a private contract member relationship within your own Private Medical Membership Association (PMA).

There are four (4) categories under which a PMA may apply:

  1. Unlicensed Medical Practitioners and Medical Researchers
  2. Licensed Practitioners under Attack for Alternative Medicine
  3. Former Licensed Practitioners
  4. Licensed or Unlicensed Medical Practitioners who need to operate in two or more or all of the 50 States.

And this is why they apply:   under the First and Fourteenth Amendments of the U.S. Constitution and equivalent provisions of your own State Constitution, you have the right to associate with fellow members and offer benefits and services that are outside of the jurisdiction, venue and authority of State and/or Federal agencies. What would be considered a criminal act outside the association (e.g., unauthorized practice of medicine) would be perfectly legal within a private association.

This right of association is not absolute. The U.S. Supreme Court has ruled in many cases that the State cannot interfere with private association activities unless the private members are being subjected to a clear danger of substantial evil that would shock a person’s moral and common sense. For example, if the private members are becoming seriously ill or injured or dying due to the so-called benefits and services of the association, then outside State and/or Federal agencies can intervene.

However, if there is no “substantial evil” resulting from the association, and the benefits and services of the private association are merely controversial, unpopular, unconventional, or lack proper endorsements and approvals, the U.S. Supreme Court again has ruled overwhelmingly that a freedom of assembly and association cannot be violated. The law is clear and our legal association has successfully fought the battles in the legal association arena for over thirty (30) years. We also have the experience of setting up Private Medical Membership Associations for practitioners for nearly ten (10) years with no interference or problems with State and/or Federal authorities to date.

ProAdvocate Group is a private membership association whose primary objective is to assist our members with establishing their respective Private Medical Membership Associations. We use the protection of the Right to Associate provided by the First Amendment to the United States Constitution to form private membership self-help associations that are (a) not open to the public, (b) do not affect a public interest, (c) and whose activities are or are not inherently benign enough to exempt them from regulation by the states’ policing powers when services are not offered to the public.

If a group of persons wishes to avail themselves of the benefits of holistic or alternative health and wellness techniques (such as herbs, homeopathic, massage and body-work, magnetics, ozone, acupuncture, nutrition, UV light, polarity and energy manipulation and numerous other systems, etc.,) they can now do so within the confines of a bona fide membership association. They can now provide these services and activities that would otherwise be regulated pursuant to various licensing acts under state policing powers when done with members of the public.

ProAdvocate Group also offers a conference in which we give the “Book, Chapter and Verse” of the law concerning licensing and the states’ policing powers, and all the seminal U.S. Supreme Court decisions.  We will prove this is the safest way for a licensed (or unlicensed) physician to get involved with many “natural alternative treatments” outside the auspices of his/her licensed practice without being exposed to the threat of discipline from respective licensing boards. As a bonus, this seminar also gives an in-depth education on licensing board disciplinary actions that no attorney would ever dare give you.

As a licensed or unlicensed health or medical practitioner, you can experience the same peace of mind and legal protection to practice your chosen area or calling without interference or sanctions. However, if one continues to operate as an unlicensed practitioner or offer services of holistic or alternative health and wellness techniques to the public, he or she could be subject to sanctions and made an example of how the state is “protecting the public.” If this were to occur, then you would have no defense and would not prevail, even if you could afford to pay huge legal fees. We have seen this many times within your field of work, and that is why we are here to help.

We welcome you to check out the benefits as a Private Medical Association with no financial risk on your part.  Please call us at 214-387-0821 for more information or you may write to the address on this web site.

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Fecal Microbiota Transplantation and the Brain Microbiota in Neurological Diseases

Clinical Endoscopy.pdf

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Clinical Observation of a Novel, Complementary, Immunotherapeutic Approach based on Ketogenic Diet, Chondroitin Sulfate, Vitamin D3, Oleic Acid and a Fermented Milk and Colostrum Product

Clinical Experience Am J Immunol-2

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Gc Protein-Derived Macrophage Activating Factor (GcMAF) and Autism: Do Clinical Results Require a Novel Interpretation?

Editorial Am J Immunol-2

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A Beginner’s Guide to the Ketogenic Diet: An Effective Way of Optimizing Your Health

http://articles.mercola.com/ketogenic-diet.aspx?utm_source=dnl&utm_medium=email&utm_content=secon&utm_campaign=20170405Z1_UCM&et_cid=DM140146&et_rid=1956589587

 

Many Americans suffer from various chronic diseases such as diabetes and obesity, and the main culprit is usually the food they eat. The standard American diet contains excessive amounts of protein and carbohydrates, neither of which is good for your health because it eventually causes you to develop insulin and leptin resistance.

As a result, you gain excess weight, develop inflammation and become prone to cellular damage.

To avoid this problem, significant changes in your diet are necessary, and the best way is inducing your body into a state of nutritional ketosis, a condition where your body burns fat as its primary fuel instead of sugar. In order to reach nutritional ketosis, you must follow a ketogenic diet. But what exactly is a ketogenic diet?

This guide will tell you everything you need to know about a ketogenic diet — how you can apply it to your lifestyle and what positives you can reap from it.

The Various Benefits of the Ketogenic Diet

A ketogenic diet is a dietary approach that focuses on minimal carbohydrates, moderate amounts of protein and high healthy fat consumption — the three keys to achieving nutritional ketosis. In fact, it’s what I recommend for most people who would like to optimize their health.

There are many reasons why you should try a ketogenic diet. It can be very beneficial for people suffering from chronic conditions, or for people who would simply like to be healthier than their current state. You’ll be excited to know that a ketogenic diet can help with the following:

Weight loss

If you’re trying to lose weight, then a ketogenic diet is one of the best ways to do it, because it helps access your body fat so that it can be shed. Obese people in particular can benefit from this method.

In one study, obese test subjects were given a low-carb ketogenic diet and a low-fat diet. After 24 weeks, researchers noted that the low-carb group lost more weight (9.4 kilograms) compared to the low-fat group (4.8 kilograms).1

Even my own body was able to feel the benefits of following a ketogenic diet. I was able to drop my weight from 180 to 164 pounds, despite eating 2,500 to 3,000 calories per day. Since then, I have increased my consumption to 3,500 to 4,000 calories just to maintain my ideal weight.

Anti-inflammatory

The human body can use sugar and fat as fuel sources. However, the latter is preferred because it is a cleaner, healthier fuel, as it releases far fewer reactive oxygen species (ROS) and secondary free radicals.

By eliminating sugar from your daily food consumption, you’re decreasing your risk of developing chronic inflammation throughout your body.

Lowering risk of cancer

One exciting discovery about the ketogenic diet is how it can help prevent cancer. Dominic D’Agostino, Ph.D., an assistant professor at the University of South Florida, recently made headway on how the ketogenic diet can help impact this dreaded disease.

D’Agostino explains that all of your cells (including cancer cells) use glucose as fuel. However, cancer cells do not have metabolic flexibility and cannot adapt to using ketones as energy, which your regular cells can. Once your body enters a state of nutritional ketosis, the cancer cells starve to death.

Increasing muscle mass

Jeff Volek, Ph.D, is a registered dietitian specializing on how a high-fat, low-carb diet can affect health and athletic performance. In one of his books, he states that ketones have a similar structure to branched-chain amino acids that can be useful for building muscle mass.

Ketones spare these amino acids, leaving higher levels of them around, which can help promote muscle mass.

Reducing Appetite

Constant hunger can cause you to consume more calories than you can burn, which can eventually lead to weight gain. A ketogenic diet can help you avoid this problem because reducing carbohydrate consumption can reduce hunger symptoms.

In one study, participants who were given a low-carbohydrate diet had reduced appetites, helping them lose weight easier.2

Lowering Insulin Levels

When you consume carbs, they are broken down into sugars in your body. In turn, this causes your blood sugar levels to rise and leads to a spike in your insulin.

Over time, you may develop insulin resistance, which can progress to type 2 diabetes. By altering your diet to a ketogenic approach, you can reduce your risk of developing type 2 diabetes.

In a study published in Nutrition & Metabolism, researchers noted that diabetics who ate low-carbohydrate ketogenic diets were able to significantly reduce their dependency on diabetes medication, and may even reverse it eventually.3

Different Types of Ketogenic Diets You Can Try

There are several variations of the ketogenic diet based on specific needs:4

Standard Ketogenic Diet (SKD)

SKD is the type I typically recommend for most people, because it is very effective. It focuses on high consumption of healthy fats (70 percent of your diet), moderate protein (25 percent) and very little carbohydrates (5 percent).5

Keep in mind that there’s no set limit to the fat, because energy requirements vary from person to person, depending on their daily physical activities.

However, majority of your calories still need to come from fats, and you still need to limit your consumption of carbohydrates and protein for it to become a standard ketogenic diet.6

Targeted Ketogenic Diet (TKD)

TKD is generally geared towards fitness enthusiasts. In this approach, you eat the entirety of your allocated carbs for the day in one meal, 30 to 60 minutes before exercise. The idea here is to use the energy provided by the carbs effectively before it disrupts ketosis.7

If you’re following this approach, I recommend that you eat carbs that are easily digestible with a high glycemic index to avoid upsetting your stomach. Then, when you’re done exercising, increase your intake of protein to help with muscle recovery, then continue consuming your fats afterwards.8

Cyclic Ketogenic Diet (CKD)

Whereas TKD is focused on fitness enthusiasts, CKD is focused more on athletes and bodybuilders. In CKD, you cycle between a normal ketogenic diet, followed by a set number of days of high carb consumption, also known as “carb-loading.”9

The idea here is to take advantage of the carbohydrates to replenish the glycogen lost from your muscles during athletic activity or working out.10

If you’re a high-level athlete or bodybuilder, CKD may be a viable method for you. It usually consists of five days of SKD, followed by two days of carb-loading. During the ketogenic cycle, carb consumption is around 50 grams, but when you get to the carb-loading cycle, the amount jumps to 450 to 600 grams. Again, this method isn’t recommended for most people who do not have a high rate of physical activity.11

High-Protein Ketogenic Diet

This method is a variant of the SKD. In a high-protein diet, you increase the ratio of protein consumption to 10 percent and reduce your healthy fat consumption by 10 percent. In a study involving obese men that tried this method, researchers noted that it helped reduce their hunger and lowered their food intake significantly, resulting in weight loss.12 If you’re overweight or obese, this may help you at first, then you can transition to SKD after you normalize your weight.

Restricted Ketogenic Diet

As mentioned earlier, a ketogenic diet can be an effective weapon against cancer. To do this, you need to be on a restricted ketogenic diet. By restricting your carbohydrate and calorie intake, your body loses glycogen and starts producing ketones that your healthy cells can use as energy. Because cancer cells cannot use these ketones, they starve to death.13

A 2010 study helps back up this claim. A 65-year old woman who was suffering from glioblastoma multiforme (GBM), an aggressive type of brain cancer, was put into a restricted ketogenic diet that started with water fasting and then proceeded to consume 600 calories a day only. After two months, her weight decreased and the ketones in her body elevated.

Furthermore, there was no discernable brain tumor tissue detected using magnetic resonance (MRI) or fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging scans.14

Put Away These Foods Before Going on a Ketogenic Diet

Before coming up with an actual ketogenic diet food list, it’s important to take a look at what you’re eating first and take out anything that’s unhealthy. This means that you have to remove sugars, starches, packaged and processed foods from your diet, because a ketogenic diet focuses on eating real, whole food.

Furthermore, avoid drinking milk because it contains the carbohydrate galactose — drinking just one glass can basically eat up your entire carb allotment for the day. In addition, avoiding milk helps lactose-intolerant people to implement the ketogenic diet. Many other products should be avoided, such as hydrogenated vegetable oils (canola, sunflower, etc.), peanut butter, soy products and sodas. They may be low on carbohydrates, but they are unhealthy and can wreak havoc on your health.

The Ideal Foods to Eat for a Ketogenic Diet

So now that you’ve taken out all the unhealthy food sources, what’s the next step? When it comes to the core of an actual ketogenic diet, remember that you need to consume only a moderate amount of protein, or about one-half gram per pound of lean body mass, each day. In addition, carbohydrates must be minimized and high-quality fats increased to serve as your new fuel source.

To ease yourself into a ketogenic diet meal plan, I usually recommend adding C8 medium-chain triglyceride (MCT) oil into your food. It’s typically more expensive than other types of MCT oil, but I prefer it more because it converts into ketones more effectively. You can start with 1 teaspoon per day, then gradually increase your consumption to 2 to 3 tablespoons per day.

If your stomach does not agree with MCT oil, you can try MCT powder, which is easier on your stomach. The table below provides a good overview of other foods rich in high-quality healthy fats:

Coconut oil Animal-based omega-3 fats from healthy sources such as wild-caught Alaskan salmon, sardines, anchovies and krill Olives and olive oil (make sure they are third-party certified because most olive oils are diluted with vegetable oils)
Raw, grass fed butter Raw nuts, such as macadamia, almonds and pecans Various seeds such as pumpkin, sesame, cumin and hemp
Avocados Grass fed meats Lard and/or tallow
Ghee (clarified butter) Raw cacao butter Organic pastured eggs

When building your ketogenic diet meal plan, it’s important to stick to green leafy vegetables because they are rich in fiber, antioxidants and various nutrients. Your best choices include broccoli, spinach, parsley, Brussels sprouts and zucchini.

While fruits are generally healthy for you, majority of them should be are avoided in a ketogenic diet because of their high amounts of sugar. However, certain berries are safe to eat in moderate quantities, such as blackberry, blueberry and cranberry, because they are rich in antioxidants that can support your health.

As for beverages, there are several you can choose from. The most important is water, but you may also drink organic black coffee (without any sweeteners or milk), which is rich in antioxidants. Coconut milk can be consumed as well, as well as herbal teas because they are rich in various antioxidants and nutrients. If you want a more extensive list, Paleo Flourish Magazine has recommendations that encompass various food groups.15

Ketogenic Recipes You Can Try

It may look like there are plenty of foods not allowed when following a ketogenic diet, but there are actually many recipes that you can cook that adhere this method. Here are three ketogenic recipes that I personally use in my daily routine:

Dr. Mercola’s Chocolate Fat Bomb Recipe

Ingredients:

  • 1 Tbsp. of black sesame seeds
  • 1 Tbsp. of flax seeds
  • 1 Tbsp. of black cumin seeds
  • 1 Tbsp. of pumpkin seeds
  • 1 Tbsp. of organic psyllium
  • 1 Tbsp. of chia seeds
  • 1 scoop of Dr. Mercola’s Organic Greens
  • 1 tsp. of calcium from ground-pastured eggshells
  • 1/2 ounce of cocoa butter
  • 1 whole avocado
  • 1 to 2 Tbsp. of medium-chain triglyceride (MCT) oil
  • 1 drop of Stevia
  • Filtered water

Procedure:

  1. Let the black sesame, flax, pumpkin and black cumin seeds soak overnight (roughly 14 hours) in a mixing bowl.
  2. Mix the remaining ingredients.
  3. Pour water to desired consistency — it can range from a liquid to pudding texture.
  4. Using an immersion blender, blend for two to five minutes for desired consistency.

Dr. Mercola’s Keto Salad Recipe

Ingredients:

  • 2 ounces of ground organic lamb
  • 1/3 red onion
  • 1 whole avocado
  • 2 to 4 ounces of sunflower seed sprouts
  • 1 to 2 Tbsp. of Dr. Mercola’s coconut oil
  • 6 pieces of anchovies (packed in salt, not oil)
  • A handful of oregano to your desired flavor (cut finely)
  • 2 to 4 ounces of fennel bulb and/or leaves
  • 2 sprigs of rosemary (chopped finely)
  • 100 grams of red pepper
  • A handful of Malabar spinach
  • 1 habanero pepper (chopped)
  • 1 Tbsp. of salmon fish roe
  • 2 to 3 ounces of grass-fed pastured butter
  • 3 ounces of fermented vegetables
  • 4 to 7 shakes of Dr. Mercola’s Himalayan salt
  • 10 to 20 of shakes ground pepper (depending on your preference)

Procedure:

  1. Gently heat the coconut oil in a frying pan.
  2. Add onions and ground organic lamb at very low heat for 20 to 25 minutes.
  3. In a separate bowl, cut and mix the remaining ingredients.
  4. After 25 minutes, add the onions to the salad and then mix it well.
  5. Rinse salt off the anchovies and soak them for five minutes.
  6. Split each anchovy into three pieces and add to the salad.
  7. Add the organic lamb to the salad.

Dr. Mercola’s Macadamia Nut Fudge Recipe

Ingredients:

  • 300 grams of cocoa butter
  • 200 grams of Dr. Mercola’s coconut oil
  • 200 grams of raw, organic-pastured butter
  • 300 grams of macadamia nuts
  • 8 full droppers of stevia (you can use Luo Han as a substitute)
  • 1 teaspoon Dr. Mercola’s organic vanilla extract

Procedure:

  1. Mix the butters and oils under low heat for three to five minutes.
  2. Once the mixture cools, add the stevia and the vanilla extract.
  3. Pour the fudge into 8-ounce wide ball jars.
  4. Spread the nuts evenly across all jars.
  5. Refrigerate until the fudge reaches the desired consistency

This recipe makes eight servings.

The Side Effects of a Ketogenic Diet

Starting a ketogenic diet can help optimize your health tremendously in many ways. But like any major dietary changes, it can have several undesirable (but not alarming) side effects, such as:

Bad Breath: Once you start on a ketogenic diet, you may notice that your breath will have an undesirable odor due to the increased acetone levels in your body.

Acetone is a ketone produced during ketosis, which is expelled in your urine and partly your breath.

On a positive note, detecting acetone in your breath is a good indicator that your ketogenic diet is working.16 You can brush your teeth and/or rinse your mouth with coconut oil to help remove the bad breath.

Short-Term Fatigue: You may begin to feel fatigue at the start of a ketogenic diet. It’s actually one of the main reasons why many people choose not to continue with this approach long before they can enjoy the benefits.17

The reason why you get tired at the start is your body is adapting from using carbohydrates for energy to healthy fats.

The transition doesn’t happen overnight, and it may take you anywhere between seven to 30 days before your body achieves full ketosis.18

Frequent Urination: During the first few days of implementing a ketogenic diet, you may notice that you’re using the bathroom more often. That’s because your body is dumping the glycogen in your liver and muscles as urine.

Furthermore, as the insulin level in your blood begins to drop, excess sodium is expelled in the form of urine as well.19

Digestive Problems: A huge shift into any dieting method can increase your risk of digestive problems, and the ketogenic diet is no exception.

Constipation is commonly reported among those who are starting out on a ketogenic diet, but it may disappear in a few weeks once your body gets used to the healthier food you’re eating.20

Sugar Cravings: You may develop intense sugar cravings as your body switches from sugar to fat for fuel. However, I encourage you not to give in to temptation.

You can practice various relaxation method such as the Emotional Freedom Techniques or yoga to take your mind away from sugary foods.21

Hair Loss: You may notice that more strands of hair getting stuck on your brush during the first few days of your ketogenic diet.

Don’t worry because this is not a big cause of concern, since hair loss can result from any major dietary changes in general. It will stop once your body achieves ketosis.22

Going into nutritional ketosis by following a ketogenic diet is one of the most radical but highly beneficial lifestyle changes you can make to improve your health. As with most dietary changes, always remember to listen to your body. If you feel any side effects other than the ones listed above, then necessary adjustments may be needed to your food intake.

Frequently Asked Questions About the Ketogenic Diet

Q: How do I go into nutritional ketosis?

A: To enter into a state of nutritional ketosis, take a look at what you’re currently eating and remove any unhealthy items such as sugary drinks and processed foods. The next step is to consume whole, organic foods that are high in healthy fats, has moderate protein and only minimal carbohydrates.

Q: How long does it take to get into ketosis?

A: Each person reacts differently to a ketogenic diet. You may experience a few side effects in the first seven to 30 days, such as constipation, fatigue and urination. But once your body normalizes, you will start feeling the benefits.

Q: How many carbs can I consume to be in a state of ketosis?

A: It’s generally recommended that only 5 percent of your daily diet is allocated to carbohydrates because if you consume more than that, your body gets thrown off ketosis. However, this is only for SKD, or the standard ketogenic diet. If you’re an athlete or a bodybuilder, you can consume more carbs without affecting ketosis by following a targeted ketogenic diet (TKD) or a cyclic ketogenic diet (CKD).

Q: How long does it take before ketosis shows results?

A: The results of ketosis can be felt as early as the first week when your body begins to dump water and carbohydrates, but the weight loss will only be minor.23 As time goes on, your body will begin to consistently shed excess fat, provided you stick to your ketogenic program.24

 

 

 

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